Interestingly, the reason the mRNA vaccines (Pfizer and Moderna) were available so quickly versus past vaccines was because the National Institute of Health (NIH) had a vaccine structure already developed in anticipation of a coronavirus outbreak. As a result, all that was needed was to sequence the virus’s genome and plug it into the structure. Therefore, the two vaccine manufacturers had vaccines ready for clinical testing five weeks after the first known case in the United States. The two vaccines tested well in the clinical trials with a 95% effective clinical trial result. People began getting vaccinated in a little less than a year of outbreak.
Dr. Fauci stated the vaccine would end the pandemic, but such was not the case. The virus mutated to various variants such a Delta and Omicron and the immunization eroded with time. Boosters were required to address the immunization erosion and vaccinated people continued to contract the disease, albeit the severity was lessened. Net, in all likelihood the virus will not go away and most likely will become like the flu with seasonal vaccination required.
Additionally, as time has passed vaccination consequences are appearing including menstrual dysregulation for young women and myocarditis in young men.
Happy Learning, Harley
THE STORY OF mRNA VACCINE DEVELOPMENT: Dr. Barney Graham was spearheading the pandemic preparedness approach at the National Instititue of Health (NIH). The coronavirus was a perfect example of being prepared for future pandemics. His team at NIH along with Jason McLellan at Dartmouth and Andrew Ward at Scripps Research, had just developed a substitution of a spike protein that worked against a variety of coronaviruses, namely MERS and SARS, and an endemic strain. This set the stage for NIH to be ready for the next time there was a novel outbreak of a coronavirus. By 2019, Graham was a diehard proponent of mRNA vaccines using a structure-based approach. He was the last author on a report in the scientific journal Science. The stage was set for their private partner Moderna to be a key player the next time a major epidemic broke out. A small handful of scientists had quietly but radically improved vaccine science just in time for the arrival of SARS-CoV-2. Source: Longshot: The Inside Story of the Race for a COVID – 19 Vaccine by David Heath (2022)
Around midday on Friday, January 3, 2020, Zhang Yongzhen, a 58-year-old infectious disease expert at the Shanghai Public Health Clinical Center, which is part of Fudan University, received a package he had been eagerly awaiting: a metal box containing a test tube with lung-washed swabs from seven different patients suffering from the new virus in a Wuhan hospital. Zhang and his colleague got right to work and didn’t stop for the next forty hours. By two a.m., on Sunday, January 5, the team had mapped the virus’s genome, or its complete set of genetic instructions, declaring the pathogen to be “very similar to SARS-type coronavirus.” They also noticed a gene producing a spike protein on the pathogen’s surface, one that resembled the one used by SARS-CoV to bind to human cells.
Zhang was torn. He was a serious scientist who had sequenced thousands of virus genomes in his career. The information would be helpful to scientists around the world. Yet Zhang also knew Chinese authorities wanted to control information about the new virus. Other government labs had decoded the same genetic material, and on January 8, Chinese leaders confirmed they were dealing with a new coronavirus. But they still sat on the genetic information. It was a warning sign to Zhang – the Chinese government didn’t want the information released, possibly because it would invite scrutiny of the country’s handling of the new virus.
Eddie Holmes, an infectious disease specialist at the University of Sidney, had written a number of scientific papers with Zhang about the evolution of various new and emerging viruses. He was desperate to learn what Zhang knew about the new pathogen. “Please call me immediately!!!” A few minutes later, Holmes saw an email with an attachment in his in-box. Holmes and Andrew Rambaut, an academic who ran a website called virological.org. had agreed to publish the sequence on his open site if Zhang ever released the information. Fifty-two minutes later, during the evening of Friday, January 10, on the East Coast of the United States, the information was available and scientists around the world were furiously downloading the sequence of the virus, which would later be named SARS-CoV-2.
“It was a weight off my shoulders,” Holmes says. Zhang was just as thrilled, at least at first. A day later, though, he began to come under pressure from Chinese authorities. They were unhappy that the nation was receiving criticism for its handling off the emerging virus, and he had released the sequence without their permission. Soon, Zhang’s lab was temporarily closed for “recertification” and funding for his research was suspended according to someone close to him.
Barney Graham wanted to act quickly. Moderna took their chosen sequence, employed some sophisticated computer software and built a mRNA molecule capable of producing the stabilized spike protein. This would be Moderna’s vaccine antigen. Source: A Shot to Save the World by Gregory Zuckerman (2021)
Eight days after Graham’s team crafted a new vaccine, SARS-CoV-2 first emerged in the U.S. in the Seattle suburb of Everett. Moderna by this point had already been making the COVID-19 vaccine for the NIH to use in animal studies and clinical trials. The company was experienced with vaccines. That experience turned out to be critical. It took the company no time at all to begin production of the COVID-19 vaccine. Graham called them on a Monday to give them the genetic code, and the next day production began. It was a quintessential illustration of mRNA’s plug-and-play capabilities and why Graham chose mRNA for a vaccine.
Now, even before the animal studies began, the NIH needed to find sites to test humans. NIH had for many years had a select number of locations that handled clinical trials for vaccines. NIH put out a notice to the 10 centers in the consortium, asking them to get ready to test the experimental concoction on humans. This was on January 27, just five weeks after the first known case of COVID-19 had been detected.
Although Moderna had a head start because of its alliance with Barney Graham, major pharmaceutical companies with vast experience in making vaccines were not far behind. Pfizer quickly became the most formidable competitor.
On May 9 researchers at Vanderbilt had results from the first eight volunteers. On May 18, Moderna made the unusual decision to release those early findings in a press release. Within days, Moderna announced plans for a 600-volunteer phase 2 trial to establish a dose. That trial was barely under way when the company started crafting the phase 3 study, which would balloon to 30,000 participants, using the most promising dose from phase 1 instead of waiting for phase 2 results. Time was of the essence. They believed the vaccine was safe; now they had to see whether it worked.
Not long after Moderna began recruiting volunteers for its final trial, the head of vaccine development for Operation Warp Speed noticed a big problem: The company wasn’t recruiting enough African Americans. The pause to recruit additional participants of color lasted two weeks and resulted in a 50% increase in Black people in the trial. It also caused Moderna to lose its front-runner status to Pfizer.
To meet the FDA threshold in the first analysis, the vaccine would have to be at least 75% effective. The data showed it had far exceeded that threshold: It was 95% effective. Finally, it was time to get the FDA to authorize the vaccines. Pfizer went first. Moderna followed just day later. Moderna’s top scientific leaders went before a panel of 21 independent scientists on an FDA advisory panel to present their data. The December 17 meeting was held remotely via webcast – and the whole world could watch.
Later in the afternoon, an FDA doctor carefully walked the independent scientists through the side effects and adverse events. She concluded that while there were a few cases of severe side effects, such as deep muscle pain, she found no safety concerns in the data. Six people in the vaccine group had died, but none of those deaths – ranging from a heart attack to suicide – was considered vaccine related. The vote of the panel was 20 yes, with one abstention – an objection to the wording, not the vaccine. Source: Longshot: The Inside Story of the Race for a COVID-19 Vaccine by David Heath.
LIFE WITH COVID-19 VACCINATIONS: Across the United States, cases, hospitalization, and deaths plunged. After peaking at 250,000 a day in January 2021, positive tests fell to 70,000 by mid-April then took another leg down and bottomed out around 12,500 a day in mid-June. Seasonality likely drove much of the early decline. Vaccines could have played only a small role – deaths fell by almost two-thirds before mid-March, when fewer than one in eight Americans were fully vaccinated. But the spring drop did appear to be vaccine related. In any case, vaccine advocates gave the shots all the credit. On May 25 CNN reported, “A vaccine marvel is bringing America back … The near-miraculous vaccines have the virus – which has ravaged the nation – in retreat. Life is being restored.”
In reality, as with everything else related to Covid, the elite’s insistence on vaccinations seemed to arise from motivations as much sociological as scientific. We know what’s best, dummies! Don’t make us tell you again! If the magic shot is good enough for us, it’s good enough for you. In any case, the vaccination campaigns made no difference. Vaccinations kept declining. Even as the elites on both left and right grew frustrated with Americans who did not want vaccines, Biden and other top Democrats, as well as public health advocates, made clear they would not impose Covid vaccine mandates or passports. As early as December 4, 2020, Biden had ruled out requiring vaccines. “I don’t think it should be mandatory,” he said.
It was a good plan. It had just one flaw. The vaccines were failing. The problems first showed up in Israel. Positive tests bottomed out in early June at around fifteen a day, a tiny number in a country of ten million people. But in the second half of June, they began rising. On June 30, Israel had almost 300 positive tests nationwide. On July 15, it had almost a thousand. By July 31, it was near 3,000. Cases had risen nearly ten-fold in a month, close to two-hundred-fold in two months. Britain followed the same trend. As cases rose, vaccine fanatics explained the shots were not really failing. Hospitalization and deaths were still low, they said. They had never promised that the vaccines would stop infection of transmission, much less eliminate or nearly eliminate Covid. They were lying. In his May 20 interview with the Washington Post – just weeks before the vaccine failure began – Fauci had said the vaccines might allow the U.S. not just to reduce Covid to a handful of cases but end it entirely. In any case, hospitalizations of vaccinated people quickly followed cases higher. By early August, deaths did, too. They had to admit vaccinated people were becoming ill and dying.
The total number of Covid deaths in Britain was far higher in August and September 2021 than in the same months in 2020 – when the vaccines hadn’t existed at all, except in clinical trials. The vaccine failure was so profound it even overwhelmed Covid’s typical seasonality. And British government statistics showed close to 70% of the dead were fully vaccinated.
But scientists needed to do much more to understand why the vaccines had failed so badly. The crisis occurred so quickly that even in September they were not sure how much of a role the Delta variant had played and how much was simply a function of waning immunity over time. As July continued the fourth American coronavirus wave began. New American cases rose relentlessly, jumping from roughly 15,000 positive tests on July 5 to roughly 165,000 in early September. Deaths inevitably followed. After bottoming around 300/day in mid-July, the topped 1,600 by mid-September. Vaccine advocates dealt with this failure in the most disingenuous way possible – by blaming it on unvaccinated people. Fauci and Surgeon General Murthy both pretended that 97 or even 99 percent of American hospitalizations and deaths were in unvaccinated people.
This statement was provably untrue. A May internal CDC paper reported that 15% of deaths in hospitals tracked by the agency were in fully vaccinate people, up from 2% in February. Data from individual states and cities also belied the 99% figure, as reported in late July. The CDC stopped counting infections in non-hospitalized vaccinated people on May 1, a bizarre decision that made tracking the performance of the vaccines nearly impossible. Fortunately, we had the international data, which made the reality of vaccine failure impossible to deny. All the spin in the world could not hide that fact that mRNA vaccine protection eroded a little more each day.
Instead of telling the truth about vaccine failure, Biden and other leaders encouraged this attitude. “Our patience is wearing thin,” Biden said on September 9. Biden seemed willing to blame any problem he faced on the unvaccinated. After almost a year of promising he would not, President Biden decided to mandate vaccines after all. On September 9, he announced that federal workplace safety rules would require businesses with more than 100 employees to make their employees be vaccinated. Never mind the patent absurdity of a rule that applied only to large employers. Never mind the fact that the rule may have overstepped Biden’s executive branch authority and faced immediate legal challenges. Never mind that the science behind the theory – that unvaccinated people represented a special threat to the vaccinated that needed to be neutralized – appeared to be murky. On August 24, researchers in Wisconsin had posted a study showing vaccinated people were just as likely to be carrying infectious virus as the unvaccinated. But the vaccinated were more likely to show no symptoms. “Even asymptomatic, fully vaccinated people might shed infectious virus,” the authors concluded.
The White House plowed ahead, even in the face of rising scientific opposition. Then an FDA advisory panel resoundingly rejected boosters for the general population on September 17 – just three days before the Biden administration said they would be available. Although the panel did recommend them for people over sixty-five, its decision marked a public rebuke for Biden and Dr. Anthony Fauci, who had publicly pushed Covid vaccines on everyone – including healthy children and adults – would continue. Source: Pandemia by Alex Berenson (2021)
The end of the story could have been how we all got vaccinated and life returned to normal. But that didn’t happen. Science didn’t defeat the pandemic. Despite a herculean effort and a surplus of vaccine, only 57% of Americans were fully vaccinated by late October 2021. More than 93 million Americans who could get the shot were still shunning it, even as new cases and deaths soared day by day. For the first time in vaccine history, science didn’t win. This time, so many people have rejected the science that the virus is still winning.
The problem has only worsened as the variants have made the virus more contagious. Now virtually everyone needs to be vaccinated to finally bring this pandemic to an end. “I think until 90% of the world has some immunity, we’re not going to be out of the pandemic,” Barney Graham said in late August 2021.
A study of health care workers and first responders showed that the Pfizer and Moderna vaccines were 66% effective at preventing infection from the Delta variant, down from 90% effectiveness early on. No one knows whether the problem is Delta or waning effectiveness of vaccines. But the FDA had approved booster shots for those age 65 and older or those with higher risks who got an mRNA vaccine. Variants remain a major concern. Source: Longshot by David Heath (2022).
During the summer of 2021, Covid – 19 staged a vicious comeback. Just when vaccines were reducing infections in the West and many people were beginning to imagine a return to a semblance of pre-pandemic normalcy, a new and especially contagious variant of SARS-CoV-2 known as the Delta variant emerged.
For most people, Covid-19 vaccines provided sufficient protection from the most dangerous effects of the variant. But large segments of the global population had yet to be inoculated, including about 99% of those on the continent of Africa. Even in the United States, only 50% or so of the population had been vaccinated, according to the CDC. The more a virus circulates in a population, the greater chance it has to mutate into a more dangerous pathogen, potentially one that’s resistant to shots, suggesting more danger could be ahead.
“The virus is not going away.” Says Stephen Hoge, Moderna’s president. Eventually it could become an endemic virus that leads to seasonal disease, like influence, as well as more painful, periodic outbreaks. Humankind will likely need to learn to live with the coronavirus, while finding creative ways to encourage unvaccinated populations to roll up their sleeves and receive shots. Source: A Shot to Save the World by Gregory Zuckerman (2021)
SOME VACCINE CONSEQUENCES: By the start of 2021, millions were getting vaccinated with mRNA vaccines, rolled out under Emergency Use Authorization. In March 2021, I began to see women on social media with appalling accounts of menstrual dysregulation after vaccination. Young healthy women were reporting two periods a month, or a period that lasted fifteen days at a time. A number of women who had been postmenopausal for years began to menstruate again, a truly bizarre symptom. Many women described horror stories related to their post-vaccination menses, agonizing cramps and the hemorrhaging of large clots of bloody tissue.
One year after YouTube censored the interview, the micro-clotting that they had hypothesized and the myocarditis of which they had warned, was abundantly and tragically confirmed. The CDC acknowledged that young men were suffering myocarditis at higher than baseline rates, post-vaccination. One year after this interview was suppressed, so many young male athletes had collapsed on the athletic field that the event was becoming a ghastly social media meme.
Also, one-year latter VAERS (the Vaccine Adverse Event Reporting System) was reporting thousands of cases of adverse reactions to the vaccine, from thrombotic events (clotting) to severe disruption of women’s menstrual cycles – and, as most reports to VAERS are voluntary, could we even know how many adverse events went unreported.
So, it’s critically important that we get this message out that the vaccine or the vaccines do not appear to be the answer that we’ve been hoping for. All I can say is what the CDC is telling us is basically 180 degrees away from what we know. The reason I think it’s so urgent, is that the vaccine companies, the health agencies are militating to vaccine children. This to me is criminal. Children have statistically zero risk from dying from COVID – 19. They do not pass the disease on to others. And yet, our governments and the pharma companies want to start vaccinating kids even two months old for no reason whatsoever. There’s no biomedical or logical reason you’d want to do something like that. Source: The Bodies of Others by Naomi Wolf (2022).